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Home  >  Journal list  >  Polymer Journal  >  Vol.48  No.7 (2016)  >  pp.801-806

Polymer Journal
<<Previous article Vol.48  No.7 (2016)   pp.801 - 806 Next article>>

Anomalous small-angle X-ray scattering study on the spatial distribution of hydrophobic molecules in polymer micelles

Ryosuke Nakanishi1, Ginpei Machida1, Masaki Kinoshita1, Kazuo Sakurai1 and Isamu Akiba1
1Department of Chemistry and Biochemistry, University of Kitakyushu, Kitakyushu, Japan

The spatial distribution of bromine-labeled hydrophobic molecules—bromobenzene (BrBz) and 4-bromobenzylalcohol (BrBzOH)—incorporated in polymer micelles of poly(N,N-dimethylaminoethyl methacrylate)-block-poly(methyl methacrylate) (PDMAEMA-b-PMMA) was investigated using anomalous small-angle X-ray scattering (ASAXS) near the Br K-edge. Both BrBz and BrBzOH were miscible with PMMA at all concentrations. ASAXS analyses revealed that BrBzOH was homogeneously dispersed in the hydrophobic PMMA core of the PDMAEMA-b-PMMA micelle, whereas BrBz was excluded from the vicinity of the core–shell interface of the PMMA core. Because of its hydrophobicity, BrBz resisted contact with water penetrating the PMMA core. Inevitably, a BrBz depletion layer formed in the vicinity of the core–shell interface. Conversely, because BrBzOH has an affinity for water due to its hydroxyl group, it can exist even in the vicinity of the core–shell interface of the PMMA core. The results of the present study suggest that the spatial distribution of hydrophobic molecules in polymer micelles can be controlled by tuning the polarity of the encapsulated species.


Received: October 08, 2015 , Revised: December 12, 2015
Accepted: January 24, 2016 , Published online: March 16, 2016
© 2016 The Society of Polymer Science, Japan

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