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Home  >  Journal list  >  Polymer Journal  >  Vol.50  No.10 (2018)  >  pp.967-974

Polymer Journal
<<Previous article Vol.50  No.10 (2018)   pp.967 - 974 Next article>>

Synthesis and thermal investigation of phosphate-functionalized acrylic materials

Yun-Fen Peng, Ashley Tsai, Ming-Hsi Huang
Yun-Fen Peng,
Ph.D. Program in Tissue Engineering and Regenerative Medicine, National Chung Hsing University, Taichung, Taiwan,
National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli, Taiwan,
Department of Oral Hygiene, Hsin Sheng Junior College of Medical Care and Management, Taoyuan, Taiwan,
Ashley Tsai,
National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli, Taiwan,
Ming-Hsi Huang,
Ph.D. Program in Tissue Engineering and Regenerative Medicine, National Chung Hsing University, Taichung, Taiwan,
National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli, Taiwan,

Functionalized acrylic materials derived from methyl methacrylate (MMA), 2-hydroxyethyl methacrylate (HEMA), and diethyl 2-(methacryloyloxy)ethyl phosphate (DMP) were synthesized by successive free-radical polymerizations using benzoyl peroxide (BPO) as the initiator and N,N-dimethyl-p-toluidine (DMpT) as the activator. NMR and GPC data showed that successful random copolymerization of MMA and DMP was carried out using the BPO-DMpT system. Moreover, the resulting products were able to react with HEMA monomer, yielding polymers with P(MMA-co-DMP)-b-PHEMA chain structures. Interestingly, the glass transition of DMP/PHEMA-containing copolymers was reduced with respect to the PMMA homopolymer. In addition, the thermal stability was enhanced with increasing DMP content in P(MMA-co-DMP) copolymers and was further enforced by incorporating PHEMA blocks. The presence of DMP/PHEMA segments should improve the thermal behavior of acrylic materials, which is of great interest in the design of versatile bone cements for total joint arthroplasty and functional coatings in targeted drug delivery.


Keyword:
Biomedical materials, Polymer characterization

Received: February 21, 2018 , Revised: April 23, 2018
Accepted: May 06, 2018 , Published online: June 06, 2018

NatureAbstract (Nature)


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